• Capturing Pre-Commercial-$tage Value

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Friends Maggie Popesco, Ph.D. and Eric Hoffman, MS are students at the University of Colorado Denver Business School and have entered the Bard Center for Entrepreneurship Business Plan Competition. They are developing a business plan around a company (Evolve Biosciences) which will target non-therapeutic biotechnology, medical device, and diagnostic IP developed at Colorado universities. Currently, [...]

It has been about a week since we last checked in on the progress of HB1001, yesterday the Colorado Bioscience bill that will inject over $26M into our ecosystem over the next five-years PASSED in the Senate!!! How exciting!!! Next stop for the legislation is to go back to the House for a final vote [...]

Setting a pre-money valuation is always an interesting step in the funding process. I’ve seen potential deals quickly unwind as a result of an entrepreneur standing firm on an irrationally perceived valuation, or an unsophisticated angel investor(s) setting a seed round price that is misaligned with the venture community. It is always a terrible shame [...]

The National Venture Capital Association released some interesting data highlighting the five fastest growing regions for attracting venture capital outside of Silicon Valley and New England. The analysis focused on the ten-year growth rates for regions across the country and ranked the fastest growing areas based upon the number of companies funded, excluding areas that [...]

Denver BioVentures emerged from stealth mode (though still no website) to announce the close of DBV Fund I, the rather impressively sized initial fund closed at $425M with their sights set exclusively on Colorado Bio. Patricia Tsanos, Ph.D., MBA who left Boston-based Adhesion Capital Partners last year wanted to spend more time at her 16,000 [...]

It has been incredibly exciting to observe the legislative process for HB1001, the Bill that may bring north of $25M to the Colorado life science ecosystem over the next five years. The Bill has marched through the House and has been working its way through the Senate passing unamended in the Appropriations committee last Friday. [...]

The Workforce Innovation Grant II RFP has been announced. The program seeks to address specific industry needs by funding innovative workforce development, training, entrepreneurship, and other industry-specific education and training partnership projects that directly lead to employment or employee advancement in bioscience. For eligibility and additional information click (here). Note: the mandatory Pre-Proposal Conference will [...]

It appears as though the link broke in yesterday’s RSS feed for the Boulder Biotechnology Company Tree .pdf. Here is the link: http://ab.rubenstein.googlepages.com/boulderbiotechtreeoct07 My apologies for any frustrations and a hearty thank you to the ever vigilant wonder-attorney Jeff Bojar, JD, MS of Snell & Wilmer who pointed out the error to me. This provides [...]

You may have seen this impressive Boulder Biotechnology Company Tree document before, perhaps even here on the CLSDF side-bar; click (here) for the .pdf. For those of you who have not previously taken a look be prepared to 1) be wow-ed and 2) have the point driven home on what an incredibly robust trajectory Boulder [...]

On the lookout for some news whilst perusing the 100+ page Form 10-K annual report filed by Replidyne (NASDAQ: RDYN) with the SEC on Friday I found the information provided on the regulatory process to be just a fantastic overview. So with some minor tweaks and a sincere appreciation to the folks in Louisville what [...]

Get those bio biz plans submitted ASAP to the 7th Annual Bard Center Business Plan Competition. The Bard competition accepts plans from students, alumni, and faculty from ALL higher education institutions and graduate programs in Colorado. So let’s see Ft. Collins and Colorado Springs get into the mix! The goals of the competition are to [...]

I like to announce every time CLSDF adds another 100 subscribers; the blog is now north of 400. Infinite appreciation to all of you for subscribing, your feedback (positive and negative) is treasured and motivating. If you find CLSDF to be of continuing value than I ask that you inform your friends and colleagues about [...]

The pros from PureTech Ventures (Boston), Accelerator Corp (Seattle) and BioAdvance (Philadelphia) spent some time yesterday setting the table of today’s current early-stage biotech investing climate and proceeded to illuminate some absolutely critical elements to incorporate while on the fund-raising trail. Without a doubt the present day funding gap or ‘valley of death’ is real [...]

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