• Capturing Pre-Commercial-$tage Value

    Welcome to Life Science Deal Flow. Our aim here is to hold my mouse to the fire by documenting the winners (and losers) of my life science trades and strategies. The focus is on a unique opportunities presented by pre-commercial stage life science entities. Don't forget to visit and subscribe to my other site, a FREE Venture Capital and competitive intelligence dBase, OnBioVC.
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UPDATE: Lots can happen between an early morning blog post and the end of the business day. In this case Omeros has set its IPO terms; 6.82M common shares offered between $10 and $12 per share. So the company is hoping to raise between $68.2 and $81.8M. The planned ticker to trade under is NASDAQ: [...]

There are a couple of upcoming seminars that are architected to yield some sophisticated insight on typically complex issues around financing early-stage life science companies. The first event courtesy of the Colorado Bioscience Association is Negotiating the Venture Term Sheet (25 September 9am, @ Cooley Godward – to RSVP or for more info click [HERE]). [...]

Tom Cech recently appeared on the CNBC pre-market morning program Squawk Box to discuss a variety of topics including the future of biomedical research, the Colorado Initiative in Molecular Biotechnology and the 1989 Nobel Laureate’s return to the University of Colorado where he will also be resuming teaching freshman chemistry. It is always fascinating to [...]

In the spirit of cool…I stumbled upon SharesPost – a sort of CraigsList meets ebay for buyers and sellers of private company equity. Talk about creating a new marketplace. Naturally there is a lot of legalese required to complete such a transaction, from investor qualification to transact, to escrow and indemnification agreements and beyond. Now [...]

Some of you may have had your head buried in a text book, an .xls file or bent over the lab bench with pipette in hand (or more likely…all three) and therefore have not heard about the Colorado Initiative in Molecular Biotechnology yet. CIMB’s mission is to foster new research, teaching, and technology development at [...]

The history of Venture Capital dates back to 1946 courtesy of the American Research and Development Corp., founded by Georges Doriot, who is subsequently considered to be the father of VC. Though many may argue the following (myself included)…The birth of biotechnology can be pegged to the 1953 presentation of the DNA double-helix structure by [...]

If you have not heard about the upcoming Rocky Mountain Life Science Investor Conference at the Ritz Carlton – Denver on 17 September, yet, you sure will get an earful about it here at CLSDF. Today’s post particularly applies to those companies who have applied to present at the RMLSIC and were not selected as [...]

Question: What do Brett Favre, LL Cool J and CLSDF have in common? Answer: Well OK, a bit of a rhetorical question…But after nearly 14-months to the day Colorado Life Science Deal Flow, version 1.5, is back! Perhaps maybe not better than ever (yet) as we effort to shake off the cobwebs and get the [...]

Dear Cherished CLSDF Readers, It is with a crashing wave of mixed emotions that I report this to be my final post as author of CLSDF. It is nearly three years to the day and over 500 posts since CLSDF launched, first as an experiment in learning about the blogosphere and new technologies yet rapidly [...]

On the heels of last weeks publications from Families USA’s Global Health Initiative report, ranking Colorado No. 4 among states that generated the most economic activity per dollar of funding from the NIH, and the 2008 Milken Institute State Technology and Science Index ranking Colorado 3rd, trailing only Massachusetts and Maryland, based on technology and [...]

I’m playing catch-up today after attending the week long BIO2008 conference last week. It was an incredible experience (again) on a variety of levels and so too was the opportunity to again be an invited conference guest blogger. Despite the technological hurdles faced I was able to get to a few postings, here is a [...]

Sitting in amazement of the logistical tango displayed by the BIO organizers on just exactly how does one feed 20,000+ attendees in a sophisticated and elegant manner, needless to say the Keynote Luncheon #1 was executed to perfection. Whilst hacking away at a blog post my PC endured the dreaded blue screen of death. What’s [...]

Having evolved into now a BIO veteran has yielded some very important lessons for a successful conference, one in particular that has resonated is – wear comfortable shoes. There is a lot of walking to be done over the four days and therefore I have elected to choose function over fashion and swap out the [...]

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