Another amazing year is in the books for me and CLSDF! What resonates most is the incredible people who I am honored to interact with on a daily basis. Sure there is the business of the business to take care of, but it is always important to recall that the intent of this community is [...]

• 283http://clsdf.com/2007/12/clsdf-2007-and-that%e2%80%99s-a-wrap/CLSDF+2007%3A+And+That%E2%80%99s+A+Wrap%212007-12-21+17%3A28%3A00admin

Many are reeling from today’s near 28% plunge in Array’s (NASDAQ: ARRY) stock price based upon the news of a failed Phase II for ARRY-886…ummm, is the street calling it failure…people please, hold on there for a moment! What exactly happened in the Mek inhibitor molecule study of this first in class novel therapy used [...]

• 282http://clsdf.com/2007/12/array-read-between-the-lines/Array%3A+Read+Between+the+Lines%212007-12-21+06%3A35%3A00admin

Another question for today…What do Amgen (NASDAQ: AMGN) and Roche (VTX: ROG.VX) have in common with Richmond, VA-based Insmed (NASDAQ: INSM) and Columbia, MD-based Martek Biosciences (NASDAQ: MATK)? Answer…they too have their state-of-the-art FDA-approved biologic commercial manufacturing facilities in Boulder. I find it interesting how Colorado is emerging as an unambiguous center of excellence in [...]

• 281http://clsdf.com/2007/12/insmed-and-colorado-manufacturing/Insmed+and+Colorado+Manufacturing2007-12-21+03%3A55%3A00admin

What do HemoGenix and Aspire Biotech have in common (insert Jeopardy theme song here)? Answer…they are working to anchor the Colorado Springs biocluster and are providing contract services for all phases of development of biomaterials, devices and applied clinical hematology. Lean all about these companies and more at the upcoming BioSoCo event sponsored by [...]

• 280http://clsdf.com/2007/12/biosoco-coming-on-strong/BioSoCo+Coming+on+Strong%212007-12-19+18%3A15%3A00admin

That’s right, Colorado Life Science Deal Flow is in heavy recruiting mode, searching the Rocky Mountain region high and low, far and wide to assemble a crack team of beat reporters in order to cast a wider net in 2008. In the New Year CLSDF will stop at nothing to look under every eppendorf tube [...]

• 279http://clsdf.com/2007/12/clsdf-we-want-you/CLSDF%3A+We+Want+You%212007-12-18+15%3A06%3A00admin

From my understanding Amgen (NASDAQ:AMGN) is manufacturing denosumab (AMG162) at the Longmont, CO facility and announced results from the first Phase III pivotal study of the monoclonal antibodies effect on bone density across the skeleton in women with non-metastatic breast cancer who were receiving adjuvant Aromatase Inhibitor therapy (AI’s lower the amount of estrogen in [...]

• 278http://clsdf.com/2007/12/amgen-denosumab-positive-piii-results/Amgen%3A+Denosumab%2C+Positive+PIII+Results2007-12-17+15%3A16%3A00admin

Make certain to sign up for the first of four sequential Bioscience Entrepreneurship Program spring mini-courses at the Bard Center. The program, directed by Arlen Meyers, MD, MBA, is offering first New Product Development and is instructed by the very talented Bill Dalke who formerly headed business development for COBE Cardiovascular. The focus of the [...]

• 277View 2 Comments...http://clsdf.com/2007/12/bard-bioscience-entrepreneurship-program/Bard+Bioscience+Entrepreneurship+Program2007-12-14+15%3A40%3A00admin

Replidyne (NASDAQ: RDYN) provided insight into their restructuring and pipeline prioritization initiatives. It is never good to hear about a local or any company for that matter have to shed people nevertheless there are a variety of silver linings in this re-org cloud. What stands out to me is the emphasis being placed upon the [...]

• 276http://clsdf.com/2007/12/good-to-not-so-great/Good+To+Not+So+Great%3F2007-12-13+00%3A48%3A00admin

Last week Aurogen (Ft. Collins) was featured on KUNC 91.5. Jim Beers of KUNC asked Northern Colorado Business Report Editor Tom Hacker about the company.
Listen to the full story on MP3 (here).
Aurogen is focused upon the unknown causation of sporadic Alzheimer’s Disease that afflicts 95% of all cases. The company asks the question [...]

• 275http://clsdf.com/2007/12/aurogen-igf%e2%80%99s-and-airplay/Aurogen%3A+IGF%E2%80%99s+and+Airplay2007-12-11+18%3A42%3A00admin

THIS IS A REPOST FROM BIOBEERS.COM
Wow…BioWest, Christmas Party and BioBeers all rolled into one fun and late evening! Our group grew by leaps and bounds attracting some 40+ folks. It was great to see a wonderful mix of Ph.D. and MBA students, faculty, bio-preneurs, start-up junkies and folks from biotech and pharma rubbing elbows [...]

• 274http://clsdf.com/2007/12/now-that-was-fun/Now+That+Was+Fun%212007-12-11+03%3A50%3A00admin

A finalist in the Venture Showcase Nanodisc, Inc. was presented by President and CEO Michael Artinger, Ph.D. Nanodiscs permit the functional solubilization of membrane-associated proteins as both drug targets and as drugs themselves. The proper packaging of membrane-associated proteins in Nanodiscs may result in better functionality of this class of protein-based drugs through improved folding, [...]

• 273http://clsdf.com/2007/12/nanodisc-drug-development-and-delivery/Nanodisc%3A+Drug+Development+and+Delivery2007-12-10+17%3A33%3A00admin

I’m still on a high from BioWest 2007 and the presentation by Jim Collins. If interested, I’ve begun a Tumblog, that is tumble-blog, sort of twitter on blog-roids, where I will be jotting stuff down not entirely related to CLSDF. If interested…I just posted a one-hour interview of Jim Collins on Charlie Rose. Take a [...]

• 272http://clsdf.com/2007/12/jim-collins-and-more-2-0-tools/Jim+Collins+and+More+2.0+Tools2007-12-10+04%3A17%3A00admin

Many thanks to Brad Feld, Managing Director of the Boulder-based Foundry Group for the golden ticket to the Feedburner Venture Capital Network, now the posts here on CLSDF will be incorporated into an aggregation of venture capital (and related bloggers) content. You may subscribe via email or RSS to all of this daily goodness (here).
Likewise [...]

• 271http://clsdf.com/2007/12/golden-ticket-to-vc-network/Golden+Ticket+to+VC+Network%212007-12-07+14%3A37%3A00admin