• Capturing Pre-Commercial-$tage Value

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If you are on the professional social networking platform, LinkedIn, you can now join the new BIO International Convention group; simply add me to your network and request an invite to join the BIO group. This year the conference will be held at the San Diego Convention Center 17–20 June. If you are not on [...]

Giddy in anticipation of the Replidyne (NASDAQ: RDYN) conference call this afternoon (2:45MST 800-435-1261 passcode 57078639) I happened upon this incredible look at the leukocyte from BioVisions @ Harvard. If you have a few minutes to watch you will likely not be disappointed. White blood cells or leukocytes are cells of the immune system which [...]

Portions of the Fitzsimons Life Science District are beginning to take shape. With an anticipated 30 to 40,000 folks to be working in the District I reckon some of them will need a place to live, well the Pauls Corporation will have an answer to that question with 21 Fitzsimons, luxury living in the heart [...]

Don’t miss the Third Butcher Symposium, Friday 16 November, part of the Colorado Initiative in Molecular Biotechnology, to be held at the Westin Westminster Hotel. The goals of the Symposium are to bring together faculty in the many areas of research related to genomics and biotechnology, to improve awareness of the relevant resources at CU, [...]

BaroFold continues to march, achieving milestone after milestone. Congratulations are in order now for striking a process development and cGMP manufacturing agreement for their lead compound BaroFeron™ (interferon beta-1b) with Avecia Biologics. Avecia will incorporate BaroFold’s PreEMT™ hydrostatic pressure technology which enables improved, safer, proprietary protein therapeutics, providing product life-cycle extensions and creating new protein [...]

Gilead (NASDAQ: GILD) announced total revenues for 3Q07 of $1.06B, up 41% percent compared to total revenues of $748.7MM for 3Q06, along with record product sales of $962MM, up 44% over 3Q06! An amazing 90-day run, but what I am most interested in is how is Letaris® (ambrisentan) faring? Now don’t quote me here because [...]

King of Pessinus, a city of Phrygia, Midas he was and everything he touched turned to gold. What then do you call the individual who accounts for nearly $4B in shareholder value creation in less than one-year? …King Freytag is he! So how does one follow-up with directing Myogen’s November 2006 $2.5B exit to Gilead [...]

AlphaSniffer has developed a highly-sensitive biosensor for detection of trace amounts (~pg/mm2) of bacteria, viruses, proteins, nucleic acids, antibodies and other biological and chemical agents in real-time and with minimal human intervention. Recently they were awarded a $200,000 SBIR grant by the NIH to develop its compact, label free, sensitive and rel-time platform that is [...]

Caveo Therapeutics (Aurora, CO) is developing a pipeline of innovative biopharmaceutical products for the treatment and cure of hematologic malignancies as well as metastatic disease. Lead candidates have been identified following in vivo preclinical studies and are currently undergoing lead optimization. The company’s technologies identify biological inhibitors that block receptors on various cell types against [...]

Amgen (NASDAQ: AMGN) announced that the company has decided to postpone indefinitely its planned design and build-out of a bulk manufacturing facility in Cork, Ireland. Amgen has two manufacturing facilities in Boulder and Longmont, Colorado. Longmont is responsible for bulk manufacture of Epogen and Aranesp. Boulder manufactures Kineret, Kepivance and a number of product candidates [...]

Pharmion (Nasdaq: PHRM) and MethylGene (TSX: MYG) announced initiation of a Phase I trial for MGCD0103, a isotype-selective histone deacetylase inhibitor in combination with Taxotere from Sanofi Aventis (NYSE: SNY) in patients with solid tumors. Taxotere is an approved chemotherapy agent marketed for use in breast, lung, prostate, gastric and head and neck cancer. Key [...]

The BioWest Conference will be here before you know it 6 and 7 December, the schedule has been finalized and looks as action packed as ever, take a look at the program (here). The event is growing by leaps and bounds and nearly 1,000 attendees are expected this year. I must admit I am really [...]

The CU Innovation Alliance Breakfast will be held Tuesday 16 October 8:00am – 10:30am at the Millennium Harvest House Hotel. Emerging CU Boulder technologies of all stages will be highlighted. Register (here)! Presenters include: Medical Informatics – An early-stage innovation from CU’s whose technology can be used to pull relevant data out of text-based medical [...]

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